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However, studies show that the consumption of herbal supplements rich in thiaminase during pregnancy (132) or alcohol exposure in utero (133) may predispose a fetus to thiamine deficiency during pregnancy and increased risk for ASD

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Amyotrophic lateral sclerosis Amyotrophic lateral sclerosis (ALS) is a swiftly advancing, fatal neurodegenerative disorder linked to mitochondrial dysfunction, 288 primarily resulting in the degeneration of motor neurons within the central nervous system (CNS) because of unmet energy demands, leading to muscle weakness and eventually respiratory failure